Hand with small amount of ZORYVE foam

Actor portrayal

Hand with small amount of ZORYVE foam

Actor portrayal

 Clearance Rates

RELIABLE SKIN CLEARANCE ANYWHERE FOR SEBORRHEIC DERMATITIS

DRAMATIC CONTROL WITH 77% IGA SUCCESS AT WEEK 82

Primary Endpoint

IGA SUCCESS AT WEEK 8

Key Secondary Endpoint

IGA OF CLEAR AT WEEK 8

CLEARANCE AS EARLY AS WEEK 21,2*

IGA Success: Clear/Almost Clear + ≥2-grade improvement

†P<0.0001, nominal.0ZORYVE (n=458)WEEK 2WEEK 4WEEK 8Vehicle (n=225) 10050% OF PATIENTS ACHIEVING IGA SUCCESS68%†41%†77%†22%42%53%
0ZORYVE (n=458)Vehicle (n=225)WEEK 2WEEK 4WEEK 8†P<0.0001, nominal.% OF PATIENTS ACHIEVING IGA SUCCESS1008060402068%†41%†77%†22%42%53%

51% WERE COMPLETELY CLEAR
(IGA=0) AT WEEK 8 IN STRATUM5

IGA = Investigator Global Assessment.

‡P=0.0001.§P<0.0001.0ZORYVE (n=304)WEEK 2WEEK 4WEEK 8Vehicle (n=153) 10050PERCENTAGE OF PATIENTS36%§6%16%‡51%§15%28%
‡P=0.0001.§P<0.0001.0ZORYVE (n=304)Vehicle (n=153)WEEK 2WEEK 4WEEK 8PERCENTAGE OF PATIENTS1008060402036%§16%‡51%§6%15%28%

*STRATUM and Trial 203 studies evaluated ZORYVE (n=458) vs vehicle (n=225) once daily for 8 weeks in patients with seborrheic dermatitis. The primary endpoint was IGA Success at Week 8, defined as a score of Clear (0) or Almost Clear (1) and a ≥2-grade improvement from baseline. Secondary endpoints in STRATUM (ZORYVE (n=304); vehicle (n=153)) included IGA of Clear (0) at Week 8 and WI-NRS Success, defined as a ≥4-point improvement for patients with a baseline score of ≥4. WI-NRS scale: 0 (no itch) to 10 (worst imaginable itch). Statistical significance was achieved as early as Week 2 for all endpoints. Data are pooled analyses of the STRATUM and Trial 203 studies.

 

IN STRATUM
51% WERE COMPLETELY CLEAR (IGA = 0) AT WEEK 8 vs 28% ON VEHICLE5

IN STRATUM

Significant itch relief at Week 8 and as early as Week 2 in STRATUM1,5

See itch data
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