Hand holding ZORYVE steroid-free cream

Actor portrayal

Hand holding ZORYVE steroid-free cream

Actor portrayal

 Itch Relief

RAPID ITCH RELIEF

RAPID, SIGNIFICANT ITCH RELIEF WITH A ONCE-DAILY, STEROID-FREE CREAM

69% of patients achieved WI-NRS Success at Week 8,
with results as early as Week 21,2

% of patients achieving WI-NRS Success

*P<0.001 vs vehicle.WEEK 2WEEK 4WEEK 6WEEK 8ZORYVE(n=447)Vehicle(n=231)54%*69%*22%20%60%*26%31%38%*
ZORYVE(n=447)Vehicle(n=231)WEEK 2WEEK 4WEEK 6WEEK 8*P<0.001 vs vehicle.54%*60%*22%20%26%69%*31%38%†*

Data are pooled analyses of the DERMIS-1 and DERMIS-2 studies.
WI-NRS = Worst Itch Numeric Rating Scale. WI-NRS Success defined as a ≥4-point improvement for patients with a baseline score ≥4. WI-NRS: 0 (no itch) to 10 (worst imaginable itch).

In a Phase 2 study

Itch-related sleep loss improved while on active treatment9†

†Based on patient-reported outcomes (PROs) data related to itch from a Phase 2b study evaluating efficacy and safety of once-daily roflumilast cream compared to vehicle for plaque psoriasis for 12 weeks. Patients were evaluated on itch-related sleep loss (IRSL) by answering a numeric scale 0 (no IRSL) to 10 (IRSL as bad as it could be) over the previous 24 hours.

Did you know? Banner ImageDid you know? Banner Image

ITCH IS THE MOST BOTHERSOME and frequently reported symptom of psoriasis, according to a 2012 population-based survey of over 2,700 patients with plaque psoriasis in North America and Europe.10

Study Design
See Before & After
View Safety Profile