Actor portrayal

Hand with dab of ZORYVE topical foam in palm coming from canister
Hand with dab of ZORYVE topical foam in palm coming from canister

Formulation

ONCE-DAILY, STEROID-FREE FOAM FOR ALL SKIN AND HAIR TYPES1

SIMPLE TREATMENT WITH ONCE-DAILY, STEROID-FREE FOAM.1

  • Simple to administer1
    • Once-daily dosing
    • Use anywhere: scalp, face, trunk, genitals, and skin folds
  • Drug delivery without disrupting the skin barrier1,5-7
    • Featuring HYDROARQ TECHNOLOGY™, a water-based foam with
      an emulsifier that doesn’t extract lipids from the skin
  • Free of sensitizing excipients and irritants1
    • No formaldehyde or formaldehyde releasers
    • No propylene glycol
    • No polyethelene glycol
    • No isopropyl alcohol
    • No ethanol
    • No fragrances
  • Contains Crodafos™ CES, a novel emulsifier with
    non-ceramide stripping properties5
    • ZORYVE is the first prescription drug to be formulated with Crodafos™ CES

Crodafos™ CES is a trademark of Croda International Plc.

Simple application

Shake

Dispense

Apply

Please see Instructions For Use for additional information.

ZORYVE is for topical use only and not for ophthalmic, oral, or intravaginal use.1

Actor portrayal

Hand holding up ZORYVE topical foam canister

SEE HOW ZORYVE IS FORMULATED WITH PURPOSE

Uniquely features HYDROARQ TECHNOLOGY™, a patient-friendly drug delivery formulation system

  • pH balanced to skin8
  • Free of sensitizing excipients and irritants, such as propylene glycol1
HYDROARQ™ suspends the low-water soluble and low-weight roflumilast molecules in a water-based emulsion.PATIENT-FRIENDLY FORMULATION – lipophilic roflumilast is absorbed by cells without disrupting the skin barrier.ACTIVE DRUG DELIVERY – Roflumilast slowly diffuses through the skin to target cells.

HYDROARQ TECHNOLOGY™

HYDROARQ TECHNOLOGY™ suspends the low-water soluble and low-weight roflumilast molecules in a water-based emulsion.2,6

PATIENT-FRIENDLY FORMULATION

The ceramides of the skin combine with the lipid bilayers of the emulsion so lipophilic roflumilast is absorbed by cells without disrupting the skin barrier.5-7

ACTIVE DRUG DELIVERY

Then the roflumilast slowly diffuses through the skin to target cells. Low water solubility, low molecular weight, and ~4-day half life contribute to once-daily dosing.1,6,7

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