






Before & After
A ONCE-DAILY, STEROID-FREE CREAM WITH THE POWER TO CLEAR ELBOWS AND KNEES, AND THE GENTLENESS FOR FACE AND FOLDS1,2
ONE PATIENT, ONE TREATMENT EVERYWHERE1
KNEE2
Baseline IGA = 3





INFRAMAMMARY CREASE2
Baseline I-IGA = 2





POWER TO CLEAR ELBOWS AND KNEES1
ELBOW2
Baseline IGA = 4





HEEL2
Baseline IGA = 3





SHIN2
Baseline IGA = 3





~50% of patients were Clear or Almost Clear (IGA 0 or 1 with any grade improvement) at Week 8 (n=519)2
GENTLENESS FOR FACE AND FOLDS2
FACE & NECK2
Baseline IGA = 3





AXILLA2
Baseline I-IGA = 3





AXILLA2
Baseline I-IGA = 3





~75% achieved intertriginous clearance (I-IGA 0 or 1 with any-grade improvement) at Week 82
~60% of patients achieved Clear intertriginous skin (I-IGA = 0 with any grade improvement) at Week 82
Meaningful clearance at Week 8
These patients met 2-grade improvement on IGA score but did not achieve Clear (0) or Almost Clear (1) at Week 8.2
KNEE2
Baseline IGA = 4


Week 8 IGA = 2
HAND2
Baseline IGA = 4


Week 8 IGA = 2


In a 2021 survey of >500 plaque psoriasis patients, more than 4 OUT OF 5 TOPICAL USERS (81%) wished they had more topical treatment alternatives to steroids.2*
*This survey was conducted online by The Harris Poll on behalf of Arcutis Biotherapeutics among US adults 18+ who have been diagnosed with psoriasis by a healthcare provider. The survey was conducted in 2021, among 507 plaque psoriasis patients. Figures were weighted where necessary to bring the data into line with actual proportions in the population using a multi-step weighting process.
ZORYVE is for topical use only and not for ophthalmic, oral, or intravaginal use.